Vancouver, April 12, 2022 – Prime Mining Corp. (“Prime” or the “Company”) (TSX-V: PRYM, OTCQB: PRMNF, Frankfurt: 04V3) announces continuing positive drill results from 26 drill holes into Guadalupe East, one of eight deposits at its wholly owned Los Reyes gold-silver project in Sinaloa State, Mexico (“Los Reyes” or the “Project”) (see Figures 1 and 2).